Differential Methylation of TCF7L2 Promoter in Peripheral Blood DNA in Newly Diagnosed, Drug-Naïve Patients with Type 2 Diabetes

TCF7L2 is the susceptibility gene for Type 2 diabetes (T2D) with the largest effect on disease risk that has been discovered to date. However, the mechanisms by which TCF7L2 contributes to the disease remain largely elusive. In addition, epigenetic mechanisms, such as changes in DNA methylation patt...

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Detalles Bibliográficos
Autores principales: Canivell, Silvia, Ruano, Elena G., Sisó-Almirall, Antoni, Kostov, Belchin, González-de Paz, Luis, Fernandez-Rebollo, Eduardo, Hanzu, Felicia A., Párrizas, Marcelina, Novials, Anna, Gomis, Ramon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051650/
https://www.ncbi.nlm.nih.gov/pubmed/24914535
http://dx.doi.org/10.1371/journal.pone.0099310

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051650/
https://www.ncbi.nlm.nih.gov/pubmed/24914535
http://dx.doi.org/10.1371/journal.pone.0099310

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