Laminin α2-Mediated Focal Adhesion Kinase Activation Triggers Alport Glomerular Pathogenesis

It has been known for some time that laminins containing α1 and α2 chains, which are normally restricted to the mesangial matrix, accumulate in the glomerular basement membranes (GBM) of Alport mice, dogs, and humans. We show that laminins containing the α2 chain, but not those containing the α1 cha...

Descripción completa

Detalles Bibliográficos
Autores principales: Delimont, Duane, Dufek, Brianna M., Meehan, Daniel T., Zallocchi, Marisa, Gratton, Michael Anne, Phillips, Grady, Cosgrove, Dominic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051676/
https://www.ncbi.nlm.nih.gov/pubmed/24915008
http://dx.doi.org/10.1371/journal.pone.0099083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051676/
https://www.ncbi.nlm.nih.gov/pubmed/24915008
http://dx.doi.org/10.1371/journal.pone.0099083

Ejemplares similares