Effects of Novel Isoform-Selective Phosphoinositide 3-Kinase Inhibitors on Natural Killer Cell Function

Phosphoinositide 3-kinases (PI3Ks) are promising targets for therapeutic development in cancer. The class I PI3K isoform p110α has received considerable attention in oncology because the gene encoding p110α (PIK3CA) is frequently mutated in human cancer. However, little is known about the function o...

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Detalles Bibliográficos
Autores principales: Yea, Sung Su, So, Lomon, Mallya, Sharmila, Lee, Jongdae, Rajasekaran, Kamalakannan, Malarkannan, Subramaniam, Fruman, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051752/
https://www.ncbi.nlm.nih.gov/pubmed/24915189
http://dx.doi.org/10.1371/journal.pone.0099486

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051752/
https://www.ncbi.nlm.nih.gov/pubmed/24915189
http://dx.doi.org/10.1371/journal.pone.0099486

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