Rapid Detection of DNMT3A R882 Mutations in Hematologic Malignancies Using a Novel Bead-Based Suspension Assay with BNA(NC) Probes

Mutations in the human DNA methyl transferase 3A (DNMT3A) gene are recurrently identified in several hematologic malignancies such as Philadelphia chromosome-negative myeloproliferative neoplasms (MPN), myelodysplastic syndromes (MDS), MPN/MDS overlap syndromes and acute myeloid leukemia (AML). They...

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Detalles Bibliográficos
Autores principales: Shivarov, Velizar, Ivanova, Milena, Naumova, Elissaveta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051762/
https://www.ncbi.nlm.nih.gov/pubmed/24914952
http://dx.doi.org/10.1371/journal.pone.0099769

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051762/
https://www.ncbi.nlm.nih.gov/pubmed/24914952
http://dx.doi.org/10.1371/journal.pone.0099769

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