New High-Affinity Monoclonal Antibodies against Shiga Toxin 1 Facilitate the Detection of Hybrid Stx1/Stx2 In Vivo

BACKGROUND: Shiga toxin-producing E. coli (STEC) are a group of common and potentially deadly intestinal pathogens expressing Shiga toxin (Stx) as a primary virulence factor. Of the two types of Stx, Stx2 is responsible for more severe symptoms during infection, while Stx1 is almost identical to the...

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Detalles Bibliográficos
Autores principales: Skinner, Craig, Patfield, Stephanie, Stanker, Larry H., Fratamico, Pina, He, Xiaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051773/
https://www.ncbi.nlm.nih.gov/pubmed/24914553
http://dx.doi.org/10.1371/journal.pone.0099854

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051773/
https://www.ncbi.nlm.nih.gov/pubmed/24914553
http://dx.doi.org/10.1371/journal.pone.0099854

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