Intestinal Cell Barrier Function In Vitro Is Severely Compromised by Keratin 8 and 18 Mutations Identified in Patients with Inflammatory Bowel Disease

Keratin 8 and 18 (K8/K18) mutations have been implicated in the aetiology of certain pathogenic processes of the liver and pancreas. While some K8 mutations (K8 G62C, K8 K464N) are also presumed susceptibility factors for inflammatory bowel disease (IBD), the only K18 mutation (K18 S230T) discovered...

Descripción completa

Detalles Bibliográficos
Autores principales: Zupancic, Tina, Stojan, Jure, Lane, Ellen Birgitte, Komel, Radovan, Bedina-Zavec, Apolonija, Liovic, Mirjana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051775/
https://www.ncbi.nlm.nih.gov/pubmed/24915158
http://dx.doi.org/10.1371/journal.pone.0099398

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051775/
https://www.ncbi.nlm.nih.gov/pubmed/24915158
http://dx.doi.org/10.1371/journal.pone.0099398

Ejemplares similares