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Endothelin-1 but not Endothelial Nitric Oxide Synthase Gene Polymorphism is Associated with Sickle Cell Disease in Africa

Sickle cell disease shows marked variability in severity and pathophysiology among individuals, probably linked to differential expression of various adhesion molecules. In this study, we investigated the differential distribution, genomic diversity and haplotype frequency of endothelial nitric oxid...

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Detalles Bibliográficos
Autores principales: Thakur, Tanya J, Guindo, Aldiouma, Cullifer, Londyn R, Li, Yi, Imumorin, Ikhide G, Diallo, Dapa A, Thomas, Bolaji N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051816/
https://www.ncbi.nlm.nih.gov/pubmed/24932102
http://dx.doi.org/10.4137/GRSB.S14836