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Astrocytic Toll-Like Receptor 3 Is Associated with Ischemic Preconditioning- Induced Protection against Brain Ischemia in Rodents

BACKGROUND: Cerebral ischemic preconditioning (IPC) protects brain against ischemic injury. Activation of Toll-like receptor 3 (TLR3) signaling can induce neuroprotective mediators, but whether astrocytic TLR3 signaling is involved in IPC-induced ischemic tolerance is not known. METHODS: IPC was mod...

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Detalles Bibliográficos
Autores principales: Pan, Lin-na, Zhu, Wei, Li, Yang, Xu, Xu-lin, Guo, Lian-jun, Lu, Qing, Wang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051824/
https://www.ncbi.nlm.nih.gov/pubmed/24914679
http://dx.doi.org/10.1371/journal.pone.0099526