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Synergistic Effects of 3D ECM and Chemogradients on Neurite Outgrowth and Guidance: A Simple Modeling and Microfluidic Framework

During nervous system development, numerous cues within the extracellular matrix microenvironment (ECM) guide the growing neurites along specific pathways to reach their intended targets. Neurite motility is controlled by extracellular signal sensing through the growth cone at the neurite tip, inclu...

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Detalles Bibliográficos
Autores principales: Srinivasan, Parthasarathy, Zervantonakis, Ioannis K., Kothapalli, Chandrasekhar R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051856/
https://www.ncbi.nlm.nih.gov/pubmed/24914812
http://dx.doi.org/10.1371/journal.pone.0099640