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Synergistic Effects of 3D ECM and Chemogradients on Neurite Outgrowth and Guidance: A Simple Modeling and Microfluidic Framework
During nervous system development, numerous cues within the extracellular matrix microenvironment (ECM) guide the growing neurites along specific pathways to reach their intended targets. Neurite motility is controlled by extracellular signal sensing through the growth cone at the neurite tip, inclu...
Autores principales: | Srinivasan, Parthasarathy, Zervantonakis, Ioannis K., Kothapalli, Chandrasekhar R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051856/ https://www.ncbi.nlm.nih.gov/pubmed/24914812 http://dx.doi.org/10.1371/journal.pone.0099640 |
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