Hippo/YAP-mediated rigidity-dependent motor neuron differentiation of human pluripotent stem cells

Our understanding of the intrinsic mechanosensitive properties of human pluripotent stem cells (hPSCs), in particular the effects that the physical microenvironment has on their differentiation, remains elusive(1). Here, we show that neural induction and caudalization of hPSCs can be accelerated by...

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Detalles Bibliográficos
Autores principales: Sun, Yubing, Yong, Koh Meng Aw, Villa-Diaz, Luis G., Zhang, Xiaoli, Chen, Weiqiang, Philson, Renee, Weng, Shinuo, Xu, Haoxing, Krebsbach, Paul H., Fu, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051885/
https://www.ncbi.nlm.nih.gov/pubmed/24728461
http://dx.doi.org/10.1038/nmat3945

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051885/
https://www.ncbi.nlm.nih.gov/pubmed/24728461
http://dx.doi.org/10.1038/nmat3945

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