Cargando…
Hippo/YAP-mediated rigidity-dependent motor neuron differentiation of human pluripotent stem cells
Our understanding of the intrinsic mechanosensitive properties of human pluripotent stem cells (hPSCs), in particular the effects that the physical microenvironment has on their differentiation, remains elusive(1). Here, we show that neural induction and caudalization of hPSCs can be accelerated by...
| Autores principales: | , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2014
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051885/ https://www.ncbi.nlm.nih.gov/pubmed/24728461 http://dx.doi.org/10.1038/nmat3945 |