NAD(+)-Dependent Activation of Sirt1 Corrects the Phenotype in a Mouse Model of Mitochondrial Disease

Mitochondrial disorders are highly heterogeneous conditions characterized by defects of the mitochondrial respiratory chain. Pharmacological activation of mitochondrial biogenesis has been proposed as an effective means to correct the biochemical defects and ameliorate the clinical phenotype in thes...

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Detalles Bibliográficos
Autores principales: Cerutti, Raffaele, Pirinen, Eija, Lamperti, Costanza, Marchet, Silvia, Sauve, Anthony A., Li, Wei, Leoni, Valerio, Schon, Eric A., Dantzer, Françoise, Auwerx, Johan, Viscomi, Carlo, Zeviani, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2014
Materias:
Short Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051987/
https://www.ncbi.nlm.nih.gov/pubmed/24814483
http://dx.doi.org/10.1016/j.cmet.2014.04.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051987/
https://www.ncbi.nlm.nih.gov/pubmed/24814483
http://dx.doi.org/10.1016/j.cmet.2014.04.001

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