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Biliverdin modulates the expression of C5aR in response to endotoxin in part via mTOR signaling

Macrophages play a crucial role in the maintenance and resolution of inflammation and express a number of pro- and anti-inflammatory molecules in response to stressors. Among them, the complement receptor 5a (C5aR) plays an integral role in the development of inflammatory disorders. Biliverdin and b...

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Detalles Bibliográficos
Autores principales: Bisht, Kavita, Wegiel, Barbara, Tampe, Jens, Neubauer, Oliver, Wagner, Karl-Heinz, Otterbein, Leo E., Bulmer, Andrew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051991/
https://www.ncbi.nlm.nih.gov/pubmed/24814708
http://dx.doi.org/10.1016/j.bbrc.2014.04.150