Finding Inhibitors of Mutant Superoxide Dismutase-1 for Amyotrophic Lateral Sclerosis Therapy from Traditional Chinese Medicine

Superoxide dismutase type 1 (SOD1) mutations cause protein aggregation and decrease protein stability, which are linked to amyotrophic lateral sclerosis (ALS) disease. This research utilizes the world's largest traditional Chinese medicine (TCM) database to search novel inhibitors of mutant SOD...

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Detalles Bibliográficos
Autores principales: Huang, Hung-Jin, Chang, Tung-Ti, Chen, Hsin-Yi, Chen, Calvin Yu-Chian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052194/
https://www.ncbi.nlm.nih.gov/pubmed/24963318
http://dx.doi.org/10.1155/2014/156276

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052194/
https://www.ncbi.nlm.nih.gov/pubmed/24963318
http://dx.doi.org/10.1155/2014/156276

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