A SNX3-dependent Retromer pathway mediates retrograde transport of the Wnt sorting receptor Wntless and is required for Wnt secretion

Wnt proteins are lipid modified glycoproteins that play a central role in development, adult tissue homeostasis and disease. Secretion of Wnt proteins is mediated by the Wnt-binding protein Wntless (Wls), which transports Wnt from the Golgi network to the cell surface for release. It has recently be...

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Detalles Bibliográficos
Autores principales: Harterink, Martin, Port, Fillip, Lorenowicz, Magdalena J., McGough, Ian J., Silhankova, Marie, Betist, Marco C., van Weering, Jan R. T., van Heesbeen, Roy G. H. P., Middelkoop, Teije C., Basler, Konrad, Cullen, Peter J., Korswagen, Hendrik C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052212/
https://www.ncbi.nlm.nih.gov/pubmed/21725319
http://dx.doi.org/10.1038/ncb2281

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052212/
https://www.ncbi.nlm.nih.gov/pubmed/21725319
http://dx.doi.org/10.1038/ncb2281

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