Biosynthetic Modularity Rules in the Bisintercalator Family of Antitumor Compounds

Diverse actinomycetes produce a family of structurally and biosynthetically related non-ribosomal peptide compounds which belong to the chromodepsipeptide family. These compounds act as bisintercalators into the DNA helix. They give rise to antitumor, antiparasitic, antibacterial and antiviral bioac...

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Detalles Bibliográficos
Autores principales: Fernández, Javier, Marín, Laura, Álvarez-Alonso, Raquel, Redondo, Saúl, Carvajal, Juan, Villamizar, Germán, Villar, Claudio J., Lombó, Felipe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052310/
https://www.ncbi.nlm.nih.gov/pubmed/24821625
http://dx.doi.org/10.3390/md12052668

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052310/
https://www.ncbi.nlm.nih.gov/pubmed/24821625
http://dx.doi.org/10.3390/md12052668

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