Carbachol-Mediated Endocytosis of NHE3 Involves a Clathrin-Independent Mechanism Requiring Lipid Rafts and Cdc42

BACKGROUND: In intestinal epithelial cells, acute regulation of the brush border Na(+)/H(+) exchanger, NHE3, usually occurs by changes in endocytosis and/or exocytosis. Constitutive NHE3 endocytosis involves clathrin. Carbachol (CCH), which elevates intracellular Ca(2+) ([Ca(2+)](i)), decreases NHE3...

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Detalles Bibliográficos
Autores principales: Zachos, Nicholas C., Alamelumangpuram, Bharath, Lee, Luke J., Wang, Peng, Kovbasnjuk, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052452/
https://www.ncbi.nlm.nih.gov/pubmed/24713550
http://dx.doi.org/10.1159/000358659

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052452/
https://www.ncbi.nlm.nih.gov/pubmed/24713550
http://dx.doi.org/10.1159/000358659

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