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Carbachol-Mediated Endocytosis of NHE3 Involves a Clathrin-Independent Mechanism Requiring Lipid Rafts and Cdc42
BACKGROUND: In intestinal epithelial cells, acute regulation of the brush border Na(+)/H(+) exchanger, NHE3, usually occurs by changes in endocytosis and/or exocytosis. Constitutive NHE3 endocytosis involves clathrin. Carbachol (CCH), which elevates intracellular Ca(2+) ([Ca(2+)](i)), decreases NHE3...
Autores principales: | Zachos, Nicholas C., Alamelumangpuram, Bharath, Lee, Luke J., Wang, Peng, Kovbasnjuk, Olga |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052452/ https://www.ncbi.nlm.nih.gov/pubmed/24713550 http://dx.doi.org/10.1159/000358659 |
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