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Humanin Rescues Cultured Rat Cortical Neurons from NMDA-Induced Toxicity Not by NMDA Receptor

Excitatory neurotoxicity has been implicated in many pathological situations and there is no effective treatment available. Humanin is a 24-aa peptide cloned from the brain of patients with Alzheimer's disease (AD). In the present study, excitatory toxicity was induced by N-methyl-D-aspartate (...

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Detalles Bibliográficos
Autores principales: Cui, Ai-Ling, Li, Jian-Zhong, Feng, Zhi-Bo, Ma, Guo-Lin, Gong, Liang, Li, Chun-Ling, Zhang, Ce, Li, Kefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052483/
https://www.ncbi.nlm.nih.gov/pubmed/24959608
http://dx.doi.org/10.1155/2014/341529