The Beneficial Effects of Valproic Acid in Thyroid Cancer Are Mediated through Promoting Redifferentiation and Reducing Stemness Level: An In Vitro Study

Valproic acid (VPA) has been identified as a histone deacetylase inhibitor, inducing differentiation in transformed cells. However, no study has shown the effect of VPA in the redifferentiation induction and stemness of anaplastic thyroid. The main objective of this study was to evaluate the efficac...

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Detalles Bibliográficos
Autores principales: Haghpanah, Vahid, Malehmir, Mohsen, Larijani, Bagher, Ahmadian, Shahin, Alimoghaddam, Kamran, Heshmat, Ramin, Ghavamzadeh, Ardeshir, Adabi, Khadijeh, Ghaffari, Seyed H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052487/
https://www.ncbi.nlm.nih.gov/pubmed/24963441
http://dx.doi.org/10.1155/2014/218763

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052487/
https://www.ncbi.nlm.nih.gov/pubmed/24963441
http://dx.doi.org/10.1155/2014/218763

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