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Gene Modification of Mesenchymal Stem Cells and Articular Chondrocytes to Enhance Chondrogenesis
Current cell based treatment for articular cartilage and osteochondral defects are hampered by issues such as cellular dedifferentiation and hypertrophy of the resident or transplanted cells. The reduced expression of chondrogenic signalling molecules and transcription factors is a major contributin...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052490/ https://www.ncbi.nlm.nih.gov/pubmed/24963479 http://dx.doi.org/10.1155/2014/369528 |