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Gene Modification of Mesenchymal Stem Cells and Articular Chondrocytes to Enhance Chondrogenesis

Current cell based treatment for articular cartilage and osteochondral defects are hampered by issues such as cellular dedifferentiation and hypertrophy of the resident or transplanted cells. The reduced expression of chondrogenic signalling molecules and transcription factors is a major contributin...

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Detalles Bibliográficos
Autores principales: Gurusinghe, Saliya, Strappe, Padraig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052490/
https://www.ncbi.nlm.nih.gov/pubmed/24963479
http://dx.doi.org/10.1155/2014/369528