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Brain mitochondria from DJ-1 knockout mice show increased respiration-dependent hydrogen peroxide consumption

Mutations in the DJ-1 gene have been shown to cause a rare autosomal-recessive genetic form of Parkinson’s disease (PD). The function of DJ-1 and its role in PD development has been linked to multiple pathways, however its exact role in the development of PD has remained elusive. It is thought that...

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Detalles Bibliográficos
Autores principales: Lopert, Pamela, Patel, Manisha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052521/
https://www.ncbi.nlm.nih.gov/pubmed/24936441
http://dx.doi.org/10.1016/j.redox.2014.04.010