SOD1 oxidation and formation of soluble aggregates in yeast: Relevance to sporadic ALS development

Misfolding and aggregation of copper–zinc superoxide dismutase (Sod1) are observed in neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS). Mutations in Sod1 lead to familial ALS (FALS), which is a late-onset disease. Since oxidative damage to proteins increases with age, it had be...

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Detalles Bibliográficos
Autores principales: Martins, Dorival, English, Ann M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052529/
https://www.ncbi.nlm.nih.gov/pubmed/24936435
http://dx.doi.org/10.1016/j.redox.2014.03.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052529/
https://www.ncbi.nlm.nih.gov/pubmed/24936435
http://dx.doi.org/10.1016/j.redox.2014.03.005

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