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Gla-Rich Protein Is a Potential New Vitamin K Target in Cancer: Evidences for a Direct GRP-Mineral Interaction

Gla-rich protein (GRP) was described in sturgeon as a new vitamin-K-dependent protein (VKDP) with a high density of Gla residues and associated with ectopic calcifications in humans. Although VKDPs function has been related with γ-carboxylation, the Gla status of GRP in humans is still unknown. Here...

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Detalles Bibliográficos
Autores principales: Viegas, Carla S. B., Herfs, Marjolein, Rafael, Marta S., Enriquez, José L., Teixeira, Alexandra, Luís, Inês M., van ‘t Hoofd, Cynthia M. R., João, Alexandre, Maria, Vera L., Cavaco, Sofia, Ferreira, Ana, Serra, Manuel, Theuwissen, Elke, Vermeer, Cees, Simes, Dina C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052551/
https://www.ncbi.nlm.nih.gov/pubmed/24949434
http://dx.doi.org/10.1155/2014/340216