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A Proposed Quantitative Index for Assessing the Potential Contribution of Reprogramming to Cancer Stem Cell Kinetics

Enrichment of cancer stem cells (CSCs) is thought to be responsible for glioblastoma multiforme (GBM) recurrence after radiation therapy. Simulation results from our agent-based cellular automata model reveal that the enrichment of CSCs may result either from an increased symmetric self-renewal divi...

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Detalles Bibliográficos
Autores principales: Gao, Xuefeng, McDonald, J. Tyson, Naidu, Mamta, Hahnfeldt, Philip, Hlatky, Lynn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052692/
https://www.ncbi.nlm.nih.gov/pubmed/24955094
http://dx.doi.org/10.1155/2014/249309