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Pronounced cohabitation of active immunoglobulin genes from three different chromosomes in transcription factories during maximal antibody synthesis

To understand the relationships between nuclear organization and gene expression in a model system, we employed three-dimensional imaging and chromatin immunoprecipitation (ChIP)-chromosome conformation capture (3C) techniques to investigate the topographies of the immunoglobulin (Ig) genes and tran...

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Detalles Bibliográficos
Autores principales: Park, Sung-Kyun, Xiang, Yougui, Feng, Xin, Garrard, William T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052762/
https://www.ncbi.nlm.nih.gov/pubmed/24888587
http://dx.doi.org/10.1101/gad.237479.114