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ParB spreading requires DNA bridging

The parABS system is a widely employed mechanism for plasmid partitioning and chromosome segregation in bacteria. ParB binds to parS sites on plasmids and chromosomes and associates with broad regions of adjacent DNA, a phenomenon known as spreading. Although essential for ParB function, the mechani...

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Detalles Bibliográficos
Autores principales: Graham, Thomas G.W., Wang, Xindan, Song, Dan, Etson, Candice M., van Oijen, Antoine M., Rudner, David Z., Loparo, Joseph J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052768/
https://www.ncbi.nlm.nih.gov/pubmed/24829297
http://dx.doi.org/10.1101/gad.242206.114