Dopamine D3 receptor dysfunction prevents anti-nociceptive effects of morphine in the spinal cord

Dopamine (DA) modulates spinal reflexes, including nociceptive reflexes, in part via the D3 receptor subtype. We have previously shown that mice lacking the functional D3 receptor (D3KO) exhibit decreased paw withdrawal latencies from painful thermal stimuli. Altering the DA system in the CNS, inclu...

Descripción completa

Detalles Bibliográficos
Autores principales: Brewer, Kori L., Baran, Christine A., Whitfield, Brian R., Jensen, A. Marley, Clemens, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052813/
https://www.ncbi.nlm.nih.gov/pubmed/24966815
http://dx.doi.org/10.3389/fncir.2014.00062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052813/
https://www.ncbi.nlm.nih.gov/pubmed/24966815
http://dx.doi.org/10.3389/fncir.2014.00062

Ejemplares similares