Cargando…

Dopamine D3 receptor dysfunction prevents anti-nociceptive effects of morphine in the spinal cord

Dopamine (DA) modulates spinal reflexes, including nociceptive reflexes, in part via the D3 receptor subtype. We have previously shown that mice lacking the functional D3 receptor (D3KO) exhibit decreased paw withdrawal latencies from painful thermal stimuli. Altering the DA system in the CNS, inclu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Brewer, Kori L., Baran, Christine A., Whitfield, Brian R., Jensen, A. Marley, Clemens, Stefan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2014
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052813/ https://www.ncbi.nlm.nih.gov/pubmed/24966815 http://dx.doi.org/10.3389/fncir.2014.00062

Ejemplares similares

Differential Dopamine D1 and D3 Receptor Modulation and Expression in the Spinal Cord of Two Mouse Models of Restless Legs Syndrome
por: Meneely, Samantha, et al.
Publicado: (2018)

Blockade of neuronal dopamine D2 receptor attenuates morphine tolerance in mice spinal cord
por: Dai, Wen-Ling, et al.
Publicado: (2016)

Anti‐ and Pro‐Nociceptive mechanisms in neuropathic pain after human spinal cord injury
por: Lütolf, Robin, et al.
Publicado: (2022)

Binge-Like Exposure to Ethanol Enhances Morphine's Anti-nociception in B6 Mice
por: Chang, Sulie L., et al.
Publicado: (2019)

Biological implications of coeruleospinal inhibition of nociceptive processing in the spinal cord
por: Tsuruoka, Masayoshi, et al.
Publicado: (2012)

Serotonergic Modulation of Nociceptive Circuits in Spinal Cord Dorsal Horn
por: Bardoni, Rita
Publicado: (2019)

The consequence of endothelial remodelling on the blood spinal cord barrier and nociception
por: Younis, Awais, et al.
Publicado: (2022)

Microstructural plasticity in nociceptive pathways after spinal cord injury
por: Kyathanahally, Sreenath P, et al.
Publicado: (2021)

Immature spinal cord neurons are dynamic regulators of adult nociceptive sensitivity
por: Rusanescu, Gabriel, et al.
Publicado: (2015)

Supraspinal nociceptive networks in neuropathic pain after spinal cord injury
por: Huynh, Vincent, et al.
Publicado: (2021)

Assessing Nociception by fMRI of the Human Spinal Cord: A Systematic Review
por: Kolesar, Tiffany A., et al.
Publicado: (2015)

Evaluation of the anti-nociceptive effects of morphine, tramadol, meloxicam and their combinations using the tail-flick test in rats
por: Foroud, Mehrzad, et al.
Publicado: (2015)

Neurotensin Attenuates Nociception by Facilitating Inhibitory Synaptic Transmission in the Mouse Spinal Cord
por: Zhang, Ming-Ming, et al.
Publicado: (2021)

Phosphoproteomics and Bioinformatics Analyses of Spinal Cord Proteins in Rats with Morphine Tolerance
por: Liaw, Wen-Jinn, et al.
Publicado: (2014)

Endoplasmic Reticulum Stress in Spinal Cord Contributes to the Development of Morphine Tolerance
por: Liu, Daiqiang, et al.
Publicado: (2018)

Intrathecal Co-administration of Morphine Facilitated the Anti-nociceptive of Bupivacaine in a Rat Model of Acute Postoperative Pain
por: Ghosh, Tamoghna, et al.
Publicado: (2022)

Morphine induces dysfunction of PINK1/Parkin-mediated mitophagy in spinal cord neurons implying involvement in antinociceptive tolerance
por: Kong, Hong, et al.
Publicado: (2019)

Central nociceptive sensitization vs. spinal cord training: opposing forms of plasticity that dictate function after complete spinal cord injury
por: Ferguson, Adam R., et al.
Publicado: (2012)

Sensitization of spinal cord nociceptive neurons with a conjugate of substance P and cholera toxin
por: Caudle, Robert M, et al.
Publicado: (2007)

Changing Balance of Spinal Cord Excitability and Nociceptive Brain Activity in Early Human Development
por: Hartley, Caroline, et al.
Publicado: (2016)

The Absence of Sensory Axon Bifurcation Affects Nociception and Termination Fields of Afferents in the Spinal Cord
por: Tröster, Philip, et al.
Publicado: (2018)

Sensory processing of deep tissue nociception in the rat spinal cord and thalamic ventrobasal complex
por: Sikandar, Shafaq, et al.
Publicado: (2017)

Early life inflammation is associated with spinal cord excitability and nociceptive sensitivity in human infants
por: Cobo, Maria M., et al.
Publicado: (2022)

The effects of chronic high-dose morphine on microgliosis and the microglial transcriptome in rat spinal cord
por: Ahlström, Fredrik HG, et al.
Publicado: (2023)

Gabapentin enhances anti-nociceptive effects of morphine on heat, cold, and mechanical hyperalgesia in a rat model of neuropathic pain
por: Hamidi, Gholam Ali, et al.
Publicado: (2014)

Protective effect of pioglitazone on morphine-induced neuroinflammation in the rat lumbar spinal cord
por: Charkhpour, Mohammad, et al.
Publicado: (2015)

PI3K mediated activation of GSK-3β reduces at-level primary afferent growth responses associated with excitotoxic spinal cord injury dysesthesias
por: Bareiss, Sonja K, et al.
Publicado: (2015)

Morphine-induced changes in the function of microglia and macrophages after acute spinal cord injury
por: Terminel, Mabel N., et al.
Publicado: (2022)

A systematic review on descending serotonergic projections and modulation of spinal nociception in chronic neuropathic pain and after spinal cord stimulation
por: Heijmans, Lonne, et al.
Publicado: (2021)

Chronic morphine administration enhances nociceptive sensitivity and local cytokine production after incision
por: Liang, DeYong, et al.
Publicado: (2008)

Short-chain fatty acid, butyrate prevents morphine-and paclitaxel-induced nociceptive hypersensitivity
por: Jessup, Dawn, et al.
Publicado: (2023)

Role of Nitric Oxide on Dopamine Release and Morphine-Dependency
por: Motahari, Amir Arash, et al.
Publicado: (2016)

Interferon alpha inhibits spinal cord synaptic and nociceptive transmission via neuronal-glial interactions
por: Liu, Chien-Cheng, et al.
Publicado: (2016)

Central Plasticity of Cutaneous Afferents Is Associated with Nociceptive Hyperreflexia after Spinal Cord Injury in Rats
por: Lee, Hyun Joon, et al.
Publicado: (2019)

Electromagnetic Field Stimulation Attenuates Phasic Nociception after Complete Spinal Cord Injury in Rats
por: Kumar, Suneel, et al.
Publicado: (2021)

New Insights on Formyl Peptide Receptor Type 2 Involvement in Nociceptive Processes in the Spinal Cord
por: Colucci, Mariantonella, et al.
Publicado: (2022)

Resting state functional connectivity differentiation of neuropathic and nociceptive pain in individuals with chronic spinal cord injury
por: Kowalski, Jesse L., et al.
Publicado: (2023)

Morphine disinhibits glutamatergic input to VTA dopamine neurons and promotes dopamine neuron excitation
por: Chen, Ming, et al.
Publicado: (2015)

Regulation of Nociceptive Plasticity Threshold and DARPP-32 Phosphorylation in Spinal Dorsal Horn Neurons by Convergent Dopamine and Glutamate Inputs
por: Buesa, Itsaso, et al.
Publicado: (2016)

Proteomic Analysis of PKCγ-Related Proteins in the Spinal Cord of Morphine-Tolerant Rats
por: Song, Zongbin, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_jcoe4e55l9oks47pcptnuu2c01