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RhoA Controls Wnt Upregulation on Microstructured Titanium Surfaces

Rough topography enhances the activation of Wnt canonical signaling in vitro, and this mediates its effects on cell differentiation. However, the molecular mechanisms underlying topography-dependent control of Wnt signaling are still poorly understood. As the small GTPase RhoA controls cytoskeletal...

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Detalles Bibliográficos
Autores principales: Lumetti, Simone, Mazzotta, Silvia, Ferrillo, Sara, Piergianni, Maddalena, Piemontese, Marilina, Passeri, Giovanni, Macaluso, Guido Maria, Galli, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052847/
https://www.ncbi.nlm.nih.gov/pubmed/24949442
http://dx.doi.org/10.1155/2014/401859