Zoledronic acid effectiveness against breast cancer metastases - a role for estrogen in the microenvironment?

Zoledronic acid (ZA) is an imidazole-containing bisphosphonate that has been extensively studied as an osteoclast inhibitor. ZA decreases bone turnover and has been effective in limiting osteolysis in metastatic cancers, including breast cancer. Recent clinical trials that demonstrated enhancement o...

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Detalles Bibliográficos
Autores principales: Steinman, Richard A, Brufsky, Adam M, Oesterreich, Steffi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053096/
https://www.ncbi.nlm.nih.gov/pubmed/23014660
http://dx.doi.org/10.1186/bcr3223

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053096/
https://www.ncbi.nlm.nih.gov/pubmed/23014660
http://dx.doi.org/10.1186/bcr3223

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