Co-expression of HER2 and HER3 receptor tyrosine kinases enhances invasion of breast cells via stimulation of interleukin-8 autocrine secretion

INTRODUCTION: The tyrosine kinase receptors HER2 and HER3 play an important role in breast cancer. The HER2/HER3 heterodimer is a critical oncogenic unit associated with reduced relapse-free and decreased overall survival. While signaling cascades downstream of HER2 and HER3 have been studied extens...

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Detalles Bibliográficos
Autores principales: Aceto, Nicola, Duss, Stephan, MacDonald, Gwen, Meyer, Dominique S, Roloff, Tim-C, Hynes, Nancy E, Bentires-Alj, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053109/
https://www.ncbi.nlm.nih.gov/pubmed/23062209
http://dx.doi.org/10.1186/bcr3329

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053109/
https://www.ncbi.nlm.nih.gov/pubmed/23062209
http://dx.doi.org/10.1186/bcr3329

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