A common copy-number breakpoint of ERBB2 amplification in breast cancer colocalizes with a complex block of segmental duplications

INTRODUCTION: Segmental duplications (low-copy repeats) are the recently duplicated genomic segments in the human genome that display nearly identical (> 90%) sequences and account for about 5% of euchromatic regions. In germline, duplicated segments mediate nonallelic homologous recombination an...

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Detalles Bibliográficos
Autores principales: Marotta, Michael, Chen, Xiongfong, Inoshita, Ayako, Stephens, Robert, Thomas Budd, G, Crowe, Joseph P, Lyons, Joanne, Kondratova, Anna, Tubbs, Raymond, Tanaka, Hisashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053137/
https://www.ncbi.nlm.nih.gov/pubmed/23181561
http://dx.doi.org/10.1186/bcr3362

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053137/
https://www.ncbi.nlm.nih.gov/pubmed/23181561
http://dx.doi.org/10.1186/bcr3362

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