Micronuclei in Bone Marrow and Liver in relation to Hepatic Metabolism and Antioxidant Response due to Coexposure to Chloroform, Dichloromethane, and Toluene in the Rat Model

Genotoxicity in cells may occur in different ways, direct interaction, production of electrophilic metabolites, and secondary genotoxicity via oxidative stress. Chloroform, dichloromethane, and toluene are primarily metabolized in liver by CYP2E1, producing reactive electrophilic metabolites, and ma...

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Detalles Bibliográficos
Autores principales: Belmont-Díaz, Javier, López-Gordillo, Ana Paulina, Molina Garduño, Eunice, Serrano-García, Luis, Coballase-Urrutia, Elvia, Cárdenas-Rodríguez, Noemí, Arellano-Aguilar, Omar, Montero-Montoya, Regina D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053251/
https://www.ncbi.nlm.nih.gov/pubmed/24949447
http://dx.doi.org/10.1155/2014/425070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053251/
https://www.ncbi.nlm.nih.gov/pubmed/24949447
http://dx.doi.org/10.1155/2014/425070

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