A TRIP230-Retinoblastoma Protein Complex Regulates Hypoxia-Inducible Factor-1α-Mediated Transcription and Cancer Cell Invasion

Localized hypoxia in solid tumors activates transcriptional programs that promote the metastatic transformation of cells. Like hypoxia-inducible hyper-vascularization, loss of the retinoblastoma protein (Rb) is a trait common to advanced stages of tumor progression in many metastatic cancers. Howeve...

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Detalles Bibliográficos
Autores principales: Labrecque, Mark P., Takhar, Mandeep K., Jagdeo, Julienne M., Tam, Kevin J., Chiu, Christina, Wang, Te-Yu, Prefontaine, Gratien G., Cox, Michael E., Beischlag, Timothy V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053355/
https://www.ncbi.nlm.nih.gov/pubmed/24919196
http://dx.doi.org/10.1371/journal.pone.0099214

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053355/
https://www.ncbi.nlm.nih.gov/pubmed/24919196
http://dx.doi.org/10.1371/journal.pone.0099214

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