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Characterization of the Xiamenmycin Biosynthesis Gene Cluster in Streptomyces xiamenensis 318

Xiamenmycin (1) is a prenylated benzopyran derivative with anti-fibrotic activity. To investigate the genetic basis of xiamenmycin biosynthesis, we performed genome mining in the xiamenmycin-producing Streptomyces xiamenensis wild-type strain 318 to identify a candidate gene cluster. The complete ge...

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Detalles Bibliográficos
Autores principales: Yang, Yong, Fu, Ling, Zhang, Jinlong, Hu, Linghan, Xu, Minjuan, Xu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053376/
https://www.ncbi.nlm.nih.gov/pubmed/24919072
http://dx.doi.org/10.1371/journal.pone.0099537