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DP-b99 Modulates Matrix Metalloproteinase Activity and Neuronal Plasticity
DP-b99 is a membrane-activated chelator of zinc and calcium ions, recently proposed as a therapeutic agent. Matrix metalloproteinases (MMPs) are zinc-dependent extracellularly operating proteases that might contribute to synaptic plasticity, learning and memory under physiological conditions. In exc...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053404/ https://www.ncbi.nlm.nih.gov/pubmed/24918931 http://dx.doi.org/10.1371/journal.pone.0099789 |