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Differential Neutralizing Activities of a Single Domain Camelid Antibody (V(H)H) Specific for Ricin Toxin’s Binding Subunit (RTB)

Ricin, a member of the A-B family of ribosome-inactivating proteins, is classified as a Select Toxin by the Centers for Disease Control and Prevention because of its potential use as a biothreat agent. In an effort to engineer therapeutics for ricin, we recently produced a collection of alpaca-deriv...

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Detalles Bibliográficos
Autores principales: Herrera, Cristina, Vance, David J., Eisele, Leslie E., Shoemaker, Charles B., Mantis, Nicholas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053406/
https://www.ncbi.nlm.nih.gov/pubmed/24918772
http://dx.doi.org/10.1371/journal.pone.0099788