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BRCA1 Silencing Is Associated with Failure of DNA Repairing in Retinal Neurocytes

Retinal post-mitotic neurocytes display genomic instability after damage induced by physiological or pathological factors. The involvement of BRCA1, an important factor in development and DNA repair in mature retinal neurocytes remains unclear. Thus, we investigated the developmental expression prof...

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Detalles Bibliográficos
Autores principales: Chen, Pei, Hu, Huan, Chen, Zhao, Cai, Xiaoxiao, Zhang, Zhang, Yang, Ying, Yu, Na, Zhang, Jing, Xia, Lei, Ge, Jian, Yu, Keming, Zhuang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053421/
https://www.ncbi.nlm.nih.gov/pubmed/24919198
http://dx.doi.org/10.1371/journal.pone.0099371