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R-Spondin 3 Regulates Dorsoventral and Anteroposterior Patterning by Antagonizing Wnt/β-Catenin Signaling in Zebrafish Embryos

The Wnt/β-catenin or canonical Wnt signaling pathway plays fundamental roles in early development and in maintaining adult tissue homeostasis. R-spondin 3 (Rspo3) is a secreted protein that has been implicated in activating the Wnt/β-catenin signaling in amphibians and mammals. Here we report that z...

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Detalles Bibliográficos
Autores principales: Rong, Xiaozhi, Chen, Chen, Zhou, Pin, Zhou, Yumei, Li, Yun, Lu, Ling, Liu, Yunzhang, Zhou, Jianfeng, Duan, Cunming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053527/
https://www.ncbi.nlm.nih.gov/pubmed/24918770
http://dx.doi.org/10.1371/journal.pone.0099514