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IKKβ in intestinal epithelial cells regulates allergen-specific IgA and allergic inflammation at distant mucosal sites

Regulation of allergy responses by intestinal epithelial cells remain poorly understood. Using a model of oral allergen sensitization in the presence of cholera toxin as adjuvant and mice with cell-specific deletion of IKKβ in intestinal epithelial cells IECs (IKKβ(ΔIEC)), we addressed the contribut...

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Detalles Bibliográficos
Autores principales: Bonnegarde-Bernard, Astrid, Jee, Junbae, Fial, Michael J., Aeffner, Famke, Cormet-Boyaka, Estelle, Davis, Ian C., Lin, Mingqun, Tomé, Daniel, Karin, Michael, Sun, Yan, Boyaka, Prosper N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053573/
https://www.ncbi.nlm.nih.gov/pubmed/23839064
http://dx.doi.org/10.1038/mi.2013.43