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On the design of clone-based haplotyping

BACKGROUND: Haplotypes are important for assessing genealogy and disease susceptibility of individual genomes, but are difficult to obtain with routine sequencing approaches. Experimental haplotype reconstruction based on assembling fragments of individual chromosomes is promising, but with variable...

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Detalles Bibliográficos
Autores principales: Lo, Christine, Liu, Rui, Lee, Jehyuk, Robasky, Kimberly, Byrne, Susan, Lucchesi, Carolina, Aach, John, Church, George, Bafna, Vineet, Zhang, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053695/
https://www.ncbi.nlm.nih.gov/pubmed/24028704
http://dx.doi.org/10.1186/gb-2013-14-9-r100