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On the design of clone-based haplotyping
BACKGROUND: Haplotypes are important for assessing genealogy and disease susceptibility of individual genomes, but are difficult to obtain with routine sequencing approaches. Experimental haplotype reconstruction based on assembling fragments of individual chromosomes is promising, but with variable...
Autores principales: | Lo, Christine, Liu, Rui, Lee, Jehyuk, Robasky, Kimberly, Byrne, Susan, Lucchesi, Carolina, Aach, John, Church, George, Bafna, Vineet, Zhang, Kun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053695/ https://www.ncbi.nlm.nih.gov/pubmed/24028704 http://dx.doi.org/10.1186/gb-2013-14-9-r100 |
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