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All Your Base: a fast and accurate probabilistic approach to base calling
The accuracy of base calls produced by Illumina sequencers is adversely affected by several processes, with laser cross-talk and cluster phasing being prominent. We introduce an explicit statistical model of the sequencing process that generalizes current models of phasing and cross-talk and forms t...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053729/ https://www.ncbi.nlm.nih.gov/pubmed/22377270 http://dx.doi.org/10.1186/gb-2012-13-2-r13 |