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Cross-enhancement of ANGPTL4 transcription by HIF1 alpha and PPAR beta/delta is the result of the conformational proximity of two response elements

BACKGROUND: Synergistic transcriptional activation by different stimuli has been reported along with a diverse array of mechanisms, but the full scope of these mechanisms has yet to be elucidated. RESULTS: We present a detailed investigation of hypoxia-inducible factor (HIF) 1 dependent gene express...

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Detalles Bibliográficos
Autores principales: Inoue, Tsuyoshi, Kohro, Takahide, Tanaka, Toshiya, Kanki, Yasuharu, Li, Guoliang, Poh, Huay-Mei, Mimura, Imari, Kobayashi, Mika, Taguchi, Akashi, Maejima, Takashi, Suehiro, Jun-ichi, Sugiyama, Akira, Kaneki, Kiyomi, Aruga, Hirofumi, Dong, Shoulian, Stevens, Junko F, Yamamoto, Shogo, Tsutsumi, Shuichi, Fujita, Toshiro, Ruan, Xiaoan, Aburatani, Hiroyuki, Nangaku, Masaomi, Ruan, Yijun, Kodama, Tatsuhiko, Wada, Youichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053749/
https://www.ncbi.nlm.nih.gov/pubmed/24721177
http://dx.doi.org/10.1186/gb-2014-15-4-r63