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Cytosine methylation changes in enhancer regions of core pro-fibrotic genes characterize kidney fibrosis development

BACKGROUND: One in eleven people is affected by chronic kidney disease, a condition characterized by kidney fibrosis and progressive loss of kidney function. Epidemiological studies indicate that adverse intrauterine and postnatal environments have a long-lasting role in chronic kidney disease devel...

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Detalles Bibliográficos
Autores principales: Ko, Yi-An, Mohtat, Davoud, Suzuki, Masako, Park, Ae Seo Deok, Izquierdo, Maria Concepcion, Han, Sang Youb, Kang, Hyun Mi, Si, Han, Hostetter, Thomas, Pullman, James M, Fazzari, Melissa, Verma, Amit, Zheng, Deyou, Greally, John M, Susztak, Katalin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053753/
https://www.ncbi.nlm.nih.gov/pubmed/24098934
http://dx.doi.org/10.1186/gb-2013-14-10-r108