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The strength of genetic interactions scales weakly with mutational effects

BACKGROUND: Genetic interactions pervade every aspect of biology, from evolutionary theory, where they determine the accessibility of evolutionary paths, to medicine, where they can contribute to complex genetic diseases. Until very recently, studies on epistatic interactions have been based on a ha...

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Detalles Bibliográficos
Autores principales: Velenich, Andrea, Gore, Jeff
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053755/
https://www.ncbi.nlm.nih.gov/pubmed/23889884
http://dx.doi.org/10.1186/gb-2013-14-7-r76