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Tissue-specific direct targets of Caenorhabditis elegans Rb/E2F dictate distinct somatic and germline programs

BACKGROUND: The tumor suppressor Rb/E2F regulates gene expression to control differentiation in multiple tissues during development, although how it directs tissue-specific gene regulation in vivo is poorly understood. RESULTS: We determined the genome-wide binding profiles for Caenorhabditis elegan...

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Detalles Bibliográficos
Autores principales: Kudron, Michelle, Niu, Wei, Lu, Zhi, Wang, Guilin, Gerstein, Mark, Snyder, Michael, Reinke, Valerie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053757/
https://www.ncbi.nlm.nih.gov/pubmed/23347407
http://dx.doi.org/10.1186/gb-2013-14-1-r5