Cargando…

p53 induces transcriptional and translational programs to suppress cell proliferation and growth

BACKGROUND: Cell growth and proliferation are tightly connected to ensure that appropriately sized daughter cells are generated following mitosis. Energy stress blocks cell growth and proliferation, a critical response for survival under extreme conditions. Excessive oncogenic stress leads to p53 ac...

Descripción completa

Detalles Bibliográficos
Autores principales: Loayza-Puch, Fabricio, Drost, Jarno, Rooijers, Koos, Lopes, Rui, Elkon, Ran, Agami, Reuven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053767/
https://www.ncbi.nlm.nih.gov/pubmed/23594524
http://dx.doi.org/10.1186/gb-2013-14-4-r32